Laboratory Equipment*Advanced Placement and AP are registered trademarks of. College Board, which was not involved in the production of, and. Category:Laboratory equipment Wikimedia Commons has media related to. Laboratory automation; Laboratory centrifuge. ScienceLab is your scientific source for laboratory equipment, specialty chemicals and science educational products. Our wide range of products in chemicals and reagents, pH meters, laboratory scales, refractometers. New tools for laboratory design and management. Abstract. The clinical laboratory is changing from a place of activity based on sample analysis to an in vitro diagnostic network. To convince our team, partners, and administrators, we need new comprehensive tools to define a strategy with limited risk of failure or conflicts. Specific quality goals should be established before choosing automated tools for sample handling, analytical systems, laboratory information systems, communication systems, or advanced technologies. A system approach maps and simplifies the process, based more on a functional study than on classical disciplines. A customer–supplier approach establishes the requirements between partners either inside or outside the laboratory. The quality system must be a management tool, linking samples, tasks, information, and documents. Quantitative simulation modeling explores different automation alternatives and their impact on laboratory workflow. Finally, integration of results in interactive semirealistic simulation tools for laboratory design or reengineering can be used as communications tools to involve laboratory professionals in the change of their practice. The clinical laboratory is changing from a place of activity based on sample analysis to an in vitro diagnostic network. This evolution is due to technological advances, a cost containment policy, and the implementation of systemic approach methods for Total Quality Management (TQM)1 (1). To face this evolution, the design of laboratories and the work of laboratory professionals must change rapidly. Technological tools are available in all the activities of the clinical laboratory, but we also need new management tools, not instruments but new methods and approaches used to convince our team, partners, and administrators to define a strategy with limited risk of failure or conflicts by crossing the frontiers between jobs and disciplines. We propose here the synthesis of our European experience in laboratory engineering. Our methods were applied to various private or hospital laboratories of various sizes, and in a specialized laboratory for clinical research in the pharmaceutical industry. Traditionally, clinical laboratory activity could be defined as a qualitative or quantitative determination of an analyte or a cell in a patient sample; analytical systems, data processing, quality control, and good know- how were necessary to perform sample analysis. Nowadays, all the steps from sample collection to the reporting of the test results to the practitioner and the patient are included in quality assurance. These steps can be presented as a quality loop, presented on Fig. Samples must then be transported to the laboratory without damage, avoiding mechanical, thermal, or delay problems. By accepting one sample, the clinical laboratory assumes that this sample is identical to the one collected from the patient. The clinical laboratory produces validated results, and passes them on with a minimal delay to the prescribing doctor and patient with some eventual service assistance in the interpretation of the results. Figure 1. Quality loop of clinical laboratory activities. This is particularly relevant as many laboratories are merging to face cost containment, thus amplifying sample handling, automation, and information processing. This enlargement of the responsibility of the clinical laboratory induces the reorganization of the clinical laboratory process, as is the case in many other activities. Considering robotic or conveyor belt technologies that were transferred from manufacturing processes to IVD activities, often discussed as the future of the clinical laboratory in Japan or in the US, we will make some comments and develop our European approach. In industry, manufacturing processes are often assembly line processes, starting from raw materials to get a final product after various operating steps. The clinical laboratory process includes different samples from one patient, and different levels of investigations involving various automated or manual methods, used in a deductive reasoning: It is a disassembly process (2). If we consider a large clinical laboratory covering all disciplines and most analyte determinations, we propose the concept of Technopole: a global structure including the management of various analytical systems and know- hows, with various logistical functions to support the IVD network. Considering the management of the analytical systems and know- hows, presented on Fig. We emphasize that so- called “full automated laboratories” (3) cover only the first part of this level of investigation. Figure 2. Management of analytical tools and know- how in the IVD network. Because of technological advances allowing the run of stat samples on the same analytical systems as nonurgent samples, stat runs performed in the core laboratory are considered more as a personalized “fast testing service” than as a dedicated workstation. Point- of- care testing and decentralized stat labs are subcontractors of the core laboratory, their activity is under the control of the quality- assurance department of the laboratory, and they are connected to the information network. At the second level, analyses are performed by various disciplines in specialized workcells including either some sophisticated equipment (flow cytometry; separative methods such as chromatography, electrophoresis, or image analysis) or activities requiring a controlled environment such as cell culture or DNA assays. Note that most of these specialized activities may be used by research and development activities in biotechnologies, bioproduction activities such as cell or gene therapy. These analytical activities must be supported by logistical and engineering activities, presented in Fig. In addition to secretaryship, documentation unit, purchasing office, washing unit, reagent preparation, and data processing, we emphasize some new activities: Figure 3. Logistical and engineering activities in the IVD network. Sample bank: Owing to various reasons like regulations, long- term monitoring of diseases, caution against medicolegal problems, and validation of new analytical methods, we store an increasing amount of samples. This storage in classical freezers is expensive, space consuming, and jeopardizes the quality of the samples in case of breakdown. We consider that a computerized sample bank with straws stored in liquid nitrogen will become a logistical activity shared by all the laboratories of the technical platform. Quality assurance, as an independent and multidisciplinary department, concerns all the steps of the quality loop from sample collection to results reporting. In addition to the implementation of quality documents, the quality- assurance department is also responsible for the metrological aspects of the laboratory (control of pipettes, weighing scales, spectrophotometers, etc.). Evaluation: New technologies must be evaluated and implemented with standardized protocols to cover technical, medical, and economical aspects in unbiased comparative evaluations involving laboratory technicians. Technical aspects include comparisons between configurations (analytical instruments + computers + environment). The required level of performance is defined in the specifications and checked when the new technology is implemented. Management and strategy to build partnerships with external partners in industry, other laboratories, research and development programs, etc. Logistical activities are performed by a part of the laboratory personnel obtained from the productivity benefits of a global management and automation programs of all the laboratories. They do not require high annual budgets, but save much money by common decisions based on a common methodology. These new activities imply a complete change of methods and work environment for concerned laboratory personnel. In 1. 98. 7, Burtis reviewed the evolution from analytical instruments to analytical systems (4), and our profession succeeded in adapting new technologies to daily work because a good basis of standardization in analytical methods was already existing, directed towards the quality of the results. Nearly 1. 0 years later, the same author described in a review (5) how the technological revolution affects the way clinical laboratories are organized, staffed, equipped, and operated. The only way to adapt ourselves to this new challenge is to be able to rethink our profession with a global quality- assurance approach issued from our analytical know- how, applied to any technology used in the IVD network, and directed towards the patient. Automated sample handling. Specific quality goals should be established between laboratory professionals before choosing automated systems: avoid mistakes requiring a new sample collection; reduce sample volume, secure identification and tracking all along the process, preservation; decrease sample handling, locate and contain biohazard (6); decrease human labor, number of tubes, and paperwork. Then, these quality goals may be applied to various steps of sample handling: sample transportation, centrifugation, detection, and aliquoting: (a) Sample transportation devices: controlled access to the samples, protection against breakage and leakage, separation between samples and documents, easy decontamination, thermal stability, tracking and traceability, time limit; (b) automated centrifuges: traceability (rotor, speed, duration, and temperature), biosafety (isolated area, closed covers for centrifugation baskets to avoid aerosols), automated detection of a possible breakage of tubes before further robotic handling, easy decontamination (7); (c) sample detection: volume, clots, hyperlipemia, hemolysis, and hyperbilirubinemia; (d) sample aliquoting: ability to use different sizes of secondary tubes, checking of identification before aliquoting, no carryover by tips or fluidic device, compatibility with sample storage.
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Area resident, Cheyenne Goss, of Newton, Illinois will be performing the National Anthem during Opening Ceremonies at Corvette Funfest. The accomplished singer/songwriter will also perform a full set on the Funfest Small Stage Saturday evening from 5: 0. Cheyenne Goss is an up- and- coming artist with considerable notoriety. The Newton, Illinois native (the same town that brought us Mike Yager) got her start after winning a national competition which won her a spot on American Idol. From there, Cheyenne's vocal talents won the hearts of judges and fans alike. Following American Idol, Cheyenne moved to Nashville, TN where she continues to chase her dream. Get your tickets for the famous Niemerg's Buffet Dinner on Saturday Night and enjoy your dinner while listening to a live performance by rising star, Cheyenne Goss. Then stick around for the Saturday Night Concert with Dennis De. Young and the Music of STYX. The Mid America Motorworks- endorsed provider of collectible car insurance returns to Funfest for VWs. Registered guests can enter to win gift certificates valued at $2. Entries for the drawings will be included in registration packets, available when you check in at Funfest Headquarters. Submit your entry at the Condon Skelly booth, for a chance to win a $2. Mid America Motorworks gift certificate. Register today to be eligible for all the giveaways at Corvette Funfest. Corvette Funfest Welcomes Back Dana Forrester. As a Corvette owner and enthusiast, Dana Forrester’s artwork reflects his personal knowledge of the Corvette and the Corvette hobby. See it in person at Corvette Funfest, where Dana will have a booth to display his latest paintings. Browse Dana’s collection of limited edition and Giclee prints to see what would look best in your home or office. Ultimate Registrations Have Sold Out! Mid America Motorworks is sorry to announce that Ultimate Registrations are Sold Out at Corvette Funfest. There are still several registration types to choose from, but we encourage you to act quickly! Premium Registrations are nearly sold out as well, for premium parking on campus, select this registration type. Choose the Exclusive Registration if you are bringing your Grand Sport to Corvette Funfest, and enjoy parking with hundreds of your fellow Grand Sport owners. If you are coming with several members of your Corvette Club, be sure to select Club Registration. Club Registration is only available for a limited time. Standard Registration still includes great perks, like Celebrity Choice Award eligibility, Thursday night Fun Run Road Tour, two free tickets to the Saturday Night Concert, and more! Register for Corvette Funfest today! Pick up your 2. 01. Commemorative Funfest Cup for only $1. |
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